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To develop an accurate method for quantifying the number of hNSC incorporated in rat brain, we performed real-time PCR on hNSC-transplanted rat brains using a target sequence for ERV-3, which is an endogenous retrovirus present with a known copy number in all human cells, but not present in rodent cells.
To examine the expression of genes encoding rare transcripts in the rat brain, we have characterized genomic DNA clones corresponding to this class.
Based on Positron emission tomography imaging using 11C-flumazenil fixation in the rat brain, we demonstrated molecular interaction between tramadol and γ-aminobutyric acid (GABA -A receptors not related to a competitive mechanism between tramadol and flumazenil on the benzodiazepine bindinGABA -A
In rat brain, we compared brainstem, right and left cortical hemispheres as well as cerebellum.
Since there was a marked difference in the production of AICD between embryonic and adult rat brain we continued by examining whether the production of Aβ also differed.
Whereas the above studies were performed in cells cultured from embryonic rat brain, we wished to explore whether ERK also played a major role in the BDNF-mediated regulation of gene expression in the mature striatum.
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To determine the localization of CB2-Rs in mouse and rat brains, we used a combination of Western blotting, immunohistochemistry and in-situ hybridization.
By applying the method to the fluctuations of the interspike interval (ISI) of spike trains recorded from neurons in the rats' brains, we find evidence for the multiple time scales in the neural activity.
Here, using patch-clamp recording and two-photon calcium imaging in rat brain slices, we demonstrate that DCN dendrites exhibit three hallmarks of active amplification of electrical signals.
Specifically, MCT1 and MCT4 expression as well as their distribution were analyzed in Sprague Dawley rat brain, and we demonstrate that both transporters are expressed in tanycytes.
Using rat brain slices, we have recently shown that hcrt/orx neurons are in turn normally excited by the multiple neurotransmitters of the arousal systems, including importantly noradrenaline [9].
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