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Thiopental anaesthesia has minimal effect on the neurochemical profile in the rat brain but substantially increases brain glucose content in the cortex as detected by in vivo 1H MRS [41].
Chronic exposure to nicotine has been shown to increase binding to high affinity nicotinic cholinergic receptors in rat brain, but the effect of this treatment on the low affinity α7 nicotinic receptors has been less well characterized.
A similar observation was made in the rat brain but only when using approximately 6 to 10 components instead of 15.
In this preclinical study, the particles collected in the rat brain, but insonation was never applied to expand the PFC5 droplets to gas to release the drug or permeabilize the blood-brain barrier.
(1996), who found the fluoxetine-induced elevation of allopregnanolone in whole male rat brain (but not all individual brain regions) to be accompanied by a fall in 5α-dihydroprogesterone concentration.
For example, microarray analysis has shown that the two OPs, chlorpyrifos and diazinon, have many similar effects on gene expression in the neonatal rat brain, but also notable disparities.
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In contrast, we found no change in hypothalamic glucokinase expression following recurrent hypoglycaemia in rat brains, but rather an increase in hexokinase expression [ 62].
Interestingly, we could detect cleavage of N-cadherin, ephrinB and p75-NTR in the embryonic rat brain membranes but not in the adult rat brain (Figure 2A).
APP and Notch1 processing was observed in both embryonic and adult rat brain membranes but to a higher extent in the embryonic rat brain membranes.
Corticosterone is synthesized in rat brain [5], but there is little evidence for glucocorticoid synthesis in songbird brain, except in molting song sparrows [34].
In this report we demonstrate γ-secretase cleavage of five substrates; APP, Notch1, N-cadherin, ephrinB and p75-NTR, in embryonic rat brain membranes but only cleavage of APP and Notch1 in adult rat brain membranes.
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