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In contrast, the two METH challenges caused decreases in rat body weights independent of the type of pretreatment (−8.4% for SMM group and −7.5% for MMM group) (Fig. 1).
Figure 1 represents the changes in the rat body weights during the experiment.
Prenatal exposure to a major polybrominated diethyl ether (BDE-99; 2,2´,4,4´,5-penta-BDE) increased mouse birth weight (Lilienthal et al. 2006), and prenatal and postnatal exposure to BDE-47 (2,2´,4,4´-tetra-BDE 2,2´,4,4´-tetra-BDE 2,2´,4,4´-tetra-BDEto puberty (when the study ended) (Suvorov et al. 2009).
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These effects were not accompanied by any change in rat body weight.
Fig. 6 Effects of MTX and MTX-CS NGs on the rat body weight.
Twenty-four day-old mand and female rats were injected with 35,600 or 106,800 Pf-728 Pfiesteria cells per kilogram of rat body weight.
After training, the rats were injected subcutaneously with fish culture water containing toxic Pfiesteria (35,600 or 106,800 cells of Pfiesteria/kg of rat body weight) or with (control) fish culture water containing no Pfiesteria.
Ninety-six (12 per group) adult female Sprague-Dawley rats were injected subcutaneously with a single dose of Pfiesteria taken from aquarium-cultured Pfiesteria (35,600 or 106,800 Pfiesteria cells per kilogram of rat body weight).
It was calculated that the human equivalent dose was 8.11 mg/kg of human body weight from dioscorin intervention of 50 mg/kg of rat body weight in the present experiment.
After overnight fasting, 18F-FDG (57.2 MBq) was administered to a normal SD rat (body weight = 319.43 g) via the tail vein under 2% isoflurane anesthesia to simulate accumulation in the brain during the steady state inhalation of 15O-CO2 gas.
Rat body weight was measured daily except weekends.
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