Sentence examples for rat as model from inspiring English sources

We chose human, mouse, and rat as model organisms that have been heavily worked on and have well annotated genomic data.

This study uses the rat as model organism because much more parameters are known for rats than for humans.

This has major implications for the use of mouse and rat as model organisms to study toxic responses, making it important to evaluate and extend this finding.

The findings from Yun You [ 28] indicated that the combined therapy of oral Chinese medicine with swimming can inhibit inflammatory factors, improve hemorheological parameters and lipoproteins in a rat AS model induced by combination of low shear stress resulted from partial ligation of common carotid artery with afterwards feeding of a hyperlipotic diet.

In this BMC Genomics supplement, Deng's laboratory and collaborators presented integrative experimental and computational genomics approaches at systems level to study the impact of RDX induced toxicity using rats as model organism [ 1].

Also in animals, as shown by our studies using the ZDF rats as model of type 2 diabetes, training (swimming) has promoted a decrease in systolic and mean blood pressure and in heart rate, together with a diminishment of differential pressure [ 33, 34], suggesting an improvement of vascular arterial compliance, with reduction in cardiac work and a left ventricular hypertrophy amelioration.

For a better understanding of the insulin effect on the central nervous system, we performed microarray-based global gene expression profiling in the hippocampus, striatum and prefrontal cortex of streptozotocin-induced and spontaneously diabetic Goto-Kakizaki rats as model animals for type 1 and type 2 diabetes, respectively.

Although global transcriptome profiling has already been carried out in Alzheimer's disease [ 21], according to our best knowledge this is the first study aiming to analyze whole genome gene expression profiles of various cerebral areas in streptozotocin-induced and spontaneously diabetic Goto-Kakizaki rats as model animals for type 1 and type 2 diabetes, respectively.

Although infants with congenital cardiac defects are mainly born at term, their brain maturity has been shown to correspond to that of a slightly preterm neonate [32, 33], justifying the choice of the P6 rat pup as model animal.

A and/or I were reported to have antioxidant, anti-hemolytic activities, angiotensin converting enzyme inhibitory activities, and anti-hypertensive activities using spontaneously hypertensive rats as models (Chen et al. 2012).

The current study used the GK and dexamethasone-treated rats as models for diabetes and hypercortisolemia, respectively.