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Since serum iPTH level was elevated in the old rat and could contribute to the desensitization to PTH, we tested this hypothesis by comparing sham-operated and PTX animals.
MSE showed antidiabetic and better ulcer healing effects compared with OMZ (antiulcer) or INS (antidiabetic) in diabetic rat and could be more effective in diabetes with concurrent gastric ulcer.
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These results suggest that caffeic acid exhibits peripheral analgesic effect in mice and rats and could be further examined for the treatment of chronic painful episodes.
These observations also indicate that ghrelin may be considered as a modulator of spermatogenesis in normal adult rats and could be potentially implicated for abnormal spermatogenesis in some testicular germ cell tumors.
Involvement of a region in the dorsal midbrain (Table 1 and Fig. 2a) was also detected in a fMRI study in rats and could possibly be attributed to activation of nociceptive bladder afferent nerves since measurements of immediate early gene expression in the brain after bladder irritation with cyclophosphamide identified this region [21].
Vasorelaxation in MS rats was significantly diminished in comparison to control rats and could be attributed to an imbalance of constricting and relaxing factors as has been previously reported (Baños et al. 1997).
Since arecoline induced expression of both LH/FSH and testosterone in control rats and could significantly recover their levels to values observed for control animals in the alloxan-induced diabetic rats, we investigated the effect of arecoline on the ultrastructure of Leydig cells.
To conclude, our findings using an animal model of sepsis, point to a dysfunction in a calcium-activated potassium channel in the hippocampus which most likely underlies plasticity deficits in rats and could be involved in sepsis-induced delirium in humans.
SMI could significantly down-regulate the activity of Ca2+ channel protein in asthmatic rat models and could possibly exhibit a preventive and therapeutic effect on asthma [ 14].
For 12,143 genes, orthologous sequences of human, mouse, rat, and cow could be obtained via their identifiers in HomoloGene using the Entrez Programming Utilities [ 37].
The metabolism was consistent with our metabolic studies in rats [11], and could be a factor to change its transport behavior.
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