Sentence examples for ras regulation from inspiring English sources

In particular, we emphasize how by combining biochemical, molecular, and imaging techniques, one can determine some of the complex array of mechanisms that have evolved to modulate the spatial and temporal dynamics of Ras regulation through these various Ras GAPs.

Therefore, we hypothetically introduced the steps 14 22 in order to take into account the effect of ErbB4 receptor-mediated signaling on Shc and Ras regulation.

To test this hypothesis, we analyzed MAPK activity and the expression of proteins under Ras regulation in wgCX4 ; cnomis1 double mutants.

However, we have less knowledge as to the possible importance of Ras regulation by transcriptional or post-translational control.

Although tumour metastasis is affected by many factors, it may be controversial as to whether RAS regulation is a key mechanism involved in suppressing tumour metastasis.

Ras regulation of NOS (with changes in both connexins and claudins) may be relevant in multiple organ systems in Rasopathy patients.

RA regulation of Tgf-beta effects in endoderm has also been suggested.

Here we present an updated and extended version of the alternative splicing model for H-Ras regulation with special emphasis on the role of p68 as regards its role in this vital transduction signal pathway tied to cell proliferation and many cancer processes.

RARE dependent oscillations in the constant presence of RA were completely abolished by RIP140 overexpression driven by a constitutive SV40 promoter that is not subject to RA regulation (Figure 1A).

As retinoids can regulate gene expression both directly, through binding of their receptors to the promoters of their regulated genes, as well as indirectly, by regulating other transcription factors which, in turn, are the final mediators of the retinoid actions, we decided to analyze if RA regulation was dependent on protein synthesis.

Importantly, RA regulation of TLR3 expression may be indirect or depend on intermediary short-lived protein(s), since incubation with CHX abrogates induction of TLR3 mRNA by RA (data not shown).