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While IGF1R inhibitors may work alone, albeit rarely, combination therapy holds promise for anti-IGF1R agents.
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"And he's a unique and rare combination of both that you rarely see in a Republican political figure, which is a very significant part of his appeal".
Fields of Dulditch, by Mary E Mann, read by Patience Tomlinson (66mins unabridged, Lark Press, £10) Sometimes, rarely, the combination of words, voice, music and atmosphere are judged to perfection.
Rarely a combination of poisonous substances other than alcohol and multiple drugs are used (Zöhre et al. 2015).
Such effects have been studied at the scale of field margins or at the wider landscape scale, but rarely in combination.
This disease usually presents with pure cerebellar ataxia or, rarely in combination with myoclonus, palatal tremor or opsoclonus myoclonus.
● Very rarely a combination of bone and skin fragility and gross joint instability will exclude either intervention.
The use of unsupervised learning with large multivariate data sets comprised of continuous data represents a rarely used combination of techniques to predict and improve patient outcomes.
Co-interventions accompanying trials with 2 liter PEG, 4 liter PEG with adjunctive medications, and NaP solution with adjunctive medications were either taken separately and only rarely in combination with the study preparation, and included magnesium citrate, metoclopramide, psyllium, bisacodyl, cisapride, ascorbic acid, senna, and simethicone.
This trend is also confirmed when using an independent test: none of the rarely occurring combinations added in later iterations turn out to be significant in the test subset.
"You rarely see a combination of factors like this one," she said.
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