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The strategy takes advantage of the rare proportion of male progeny (XO, < 0.2%) that naturally arises in wild-type hermaphroditic (XX) populations as a result of a meiotic segregation error of the X chromosome (Hodgkin et al. 1979).
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Although rare, the proportion of IMD caused by serogroup B has increased and currently causes most IMD in Ontario, with infants having the highest risk of disease.
Because these alleles are rare, the proportion of breast cancer in the population that may be explained by these genotypes is low.
Our methods clearly show enhanced statistical power over existing methods for a wide range of population-attributable risk, percentage of disease-contributing rare variants, and proportion of rare alleles working in different directions.
Irrigation is still rare, and the proportion of Ethiopians living in absolute poverty has fallen only slightly from 45.5% in 1996 to 44.2% in 2000, according to the IMF.
In the USA, the focus of safety policy was promotion or legislation of helmet use, but bike-specific facilities were rare, and the proportion of trips by bicycle was about 1%.
Although we found that serious physical injuries were rare, a high proportion of the victims of workplace violence, especially those who had been verbally abused (with no physical contact), experienced mental stress.
Although mutant BRAF (v-Raf murine sarcoma viral oncogene homolog B1) inhibitors such as vemurafenib and dabrafenib have achieved unprecedented clinical responses in the treatment of melanomas with activating mutations in BRAF, complete remission is rare and a proportion of mutant BRAF melanomas are less responsive to the inhibitors.
Using the data of the 1000 Genomes Project (http://www.1000genomes.org), future GWA studies might include rare variants to ensure that a high proportion of rare SNPs are captured (61).
The repression of the argU, ileX, ileY, and proL rare tRNAs by Hha should be physiologically relevant for the translation of proteins with a high proportion of rare AGG, AGA, ATA, and CCC rare codons, respectively.
Today the production of permanent magnets consumes the largest proportion of rare earth elements, with 40% of the rare earth-based magnets used for generators and other electrical machines.
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