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Sarcoidosis often involves the septum (particularly basal portion) and left ventricular wall with rare involvement of the right ventricle and papillary muscles [32].
Skin thickening is well demonstrated, as is rare involvement of the nipple and nipple areolar complex.
The most frequently affected arteries are the subclavian, axillary, femoral, popliteal, tibial and peroneal, with rare involvement of coronary arteries [45].
Rare involvement of the body of the uterus and the cervix (Fig. 13) has been reported.
Although previous histopathological studies on specimens of human prostate carcinoma showed a relatively rare involvement of malignant glands by lymphocytes (Vesalainen et al, 1994; McArdle et al, 2004), the possible effects of tumour neovasculature were not considered.
In addition to the SCC differentiation and more pronounced male preponderance, a low mean age at diagnosis and rare involvement of the trigonal region characterize BC in Africa and the Middle East [ 3].
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Reports of rare abdominal involvement have been published [28].
Primary leiomyosarcoma of the pancreas has a high incidence of distant metastases and regional invasion, with rare lymphatic involvement [28], which could be the key point to differential diagnosis [36].
Gliomatosis cerebri is a rare, diffuse involvement of the central nervous system by a malignant glioma that permeates the brain extensively without destroying the neural architecture and involves more than two lobes.
NPM1 haploinsufficiency and mutation appear to exert very different effects (Figure 4) as patients with NPM1 mutated-AML have normal karyotype, rare TP53 involvement, good prognosis if FLT3-ITD mutations are absent, and a predominance of females [2], [25], [26].
Our case was unique in that osteomalacia developed as a result of the rare renal involvement of asymptomatic PBC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com