The phrase "rare frequency" is grammatically correct and can be used in written English.
It means something that occurs infrequently or at a low rate. Example: "The meteorological phenomenon known as a 'blood moon' happens with rare frequency, only occurring once every few years."
By contrast, Updike must have lightheartedly realized that he was calling upon "lambent" and "lambency" with rare frequency.
We measured MMN generated to rare frequency, duration, intensity and spatial deviant sounds randomly occurring in a stream of identical repeating "standard" sounds.
Genome-wide association studies applied to schizophrenia have successfully identified discrete risk variants of common and rare frequency, but the functional characterization and neurobiological import of these loci remain to be elucidated.
We propose a new algorithm, called inverse weight selection (IWS), that preferentially selects individuals based on the cumulative presence of rare frequency haplotypes to maximize the efficiency of WGS surveys.
Another possibility is that the nontargeted MiPSCs also included those variants at a rare frequency, but their frequency accumulated in the mito-TALEN-induced mtDNA heteroplasmy shifts.
However, the vast majority of identified CNVs were of rare frequency (<5 %) and were not statistically associated with asthma. 2 CNVs near NOS1 and SERPINA3 were modestly association with asthma and they were unlikely to explain the previously identified associations between SNP and asthma.
Altogether, these results confirm that pre-treatment samples already contain resistant subclones before the initiation of targeted inhibition of BTK, albeit at rare frequencies.
The widespread distribution and unexpectedly high density of CARcs stands in apparent contradiction with the rare frequencies reported by numerous groups using FC techniques30,31,43.
A central bottleneck is that most recurrently mutated genes in cancer are found mutated in fewer than 5% of patients and most individual variants are found at exceedingly rare frequencies.
The distributions of polymorphism frequencies at nonsynonymous and 5′-UTR sites were the most skewed toward rare frequencies relative to synonymous polymorphisms (Wilcoxon rank-sum test versus synonymous sites: Z = 7.98, P = 1.5e-15 and Z = 7.28, P = 3.2e-13, respectively).
Even with this correction, GWAS has limited power to detect allele variants present in rare frequencies (Brachi et al. 2011; Wallace et al. 2014; Zuk et al. 2014) or loci with multiple allelic variants (Zhang et al. 2012).
