AICAR is rapidly transported into cells, probably by the adenosine transporter (30), and phosphorylated to form the AMP mimetic 5-aminoimidazole-4-carboxamine ribonucleoside monophosphate, which directly activates AMPK.
An important consideration is that adenosine is rapidly transported into red cells via the equilibrative nucleoside transporter and this makes the adenosine unavailable to interact with platelets.
Thymidine is rapidly transported into the cell from the extracellular fluid using non-energy-dependent nucleoside transporters and active, Na+-dependent carriers.
In all cases, lactic acid must be rapidly transported across the plasma membrane and this is mediated by proton-linked monocarboxylate transporters (MCTs) that in mammals are the part of a family of related transporter proteins containing 14 members.
But much like humans, cattle that are rapidly transported to altitudes greater than 5,000 feet, are vulnerable to health problems.
But true to its Shakespearean origins, the work's leading couples are rapidly transported to a world of delirium by the mischievous magic of Puck.
The presence of specialized mechanisms of elimination in higher animals enables wastes to be rapidly transported to the exterior surface of the body (see below Vertebrate excretory systems).
Any substance that preferentially dissolves in the mobile liquid is more rapidly transported in the direction of flow than is a substance that has greater affinity for the stationary liquid.
Within the stable interiors of old continents, geothermal gradients of 25 to 35 °C per kilometre are more typical, and in zones of active subduction, where the relatively cold oceanic crust is rapidly transported to great depths, geothermal gradients range from 10 to 20 °C per kilometre.
The latter process occurs either when hot magma intrudes and alters the thermal state of a stationary rock or when the rock is rapidly transported by tectonic processes (e.g., thrust faulting or large-scale folding) into a new depth-temperature regime in, for example, areas of collision between two continents.
