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This solution was preferred because it turned out to be an excellent alternative to database for retrieving rapidly expression values for the selected TS.
All 4 traits showed among-individual variance in mean levels of expression across the adult lifespan, but no significant differences in how rapidly expression changed with age.
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We found that treatment of PTGER4 cells with 100 nM PGE2 rapidly induced expression of PTGER4 at all time points investigated (Figure 6A, P<0.001).
Quiescent human fibroblasts rapidly increase expression of the c-Fos proto-oncoprotein when stimulated by serum mitogens, but this response is lost upon senescence [4], [7].
Of the Klfs which repress transcription, endothelin-1 rapidly downregulated expression of Klf3, Klf11 and Klf15.
We were interested in a related question: How rapidly can expression profiles diverge among duplicated genes?
miR-17-3p negatively regulates FLK-1-mediated angiogenesis in ECs by rapidly downregulating expression via a 21 bp fragment from the FLK-1 3′-UTR [ 88].
Previous work [ 47] has demonstrated that low-magnitude cyclic and sustained large-magnitude stretch can rapidly induce expression of extracellular signal-related kinase (ERK1/2-MAPK).
In epithelial cells from the skin, lung, and breast, TGF- β rapidly elevates expression of the Cdk4/6 inhibitor p15INK4B (Hannon and Beach, 1994).
The perivascular space is likely the primary site of immune complex-induced inflammation as we find constitutive and then rapidly increased expression of FcγR on perivascular macrophages.
In response to B. cinerea, differentially expressed transcripts grouped into four categories: genes whose expression rapidly increased then rapidly decreased, genes whose expression rapidly increased and plateaued, genes whose expression continually increased, and genes with decreased expression.
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