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Cancer is a term used to define a collective set of rapidly evolving cells with immortalized replication, altered epimetabolomes and patterns of longevity.
They determined the probability of the success and failure of biomedical intervention against rapidly evolving cells.
The bioinformatic procedure is of general applicability to fine genotyping, including studies of heterogeneous viral populations, genetic changes in virus, bacteria, and genes of rapidly evolving cells, such as tumoral cells.
Interestingly, in evolving bacterial populations, sporadic evolving mutator phenotype strains can occasionally outcompete resident nonmutator strains (Sniegowski et al. 1997) producing a population of rapidly evolving cells (Barrick et al. 2009).
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It is thus likely that eukaryotes evolved from a small population of prokaryotes with endosymbionts: unstable, rapidly evolving, protosexual cells.
Germ cell-expressed genes and somatic cell-expressed genes evolve at different rates, and we speculate that the greater conservation of somatic factors would require a correspondingly greater conservation of target sites whereas more rapidly evolving germ cell factors might coevolve with rapidly changing regulatory sites.
The need for free information flow within the academic community is especially true for rapidly evolving fields such as cell signaling, which is now entering a new and exciting era of development.
The production of cytotoxic T cells with specificity for cancer cells is a rapidly evolving branch of cancer therapeutics.
Fuel cells is a rapidly evolving technology with applications in many industries including transportation, and both portable and stationary power generation.
The concept of tissue and cell guidance is rapidly evolving as more information regarding the effect of the microenvironment on cellular function and tissue morphogenesis become available.
While the knowledge of muscle cells may already benefit of the present study, it is likely that the microgenomic approach will become more and more attractive for studies on muscle heterogeneity, plasticity and diseases, as single cell technologies are rapidly evolving and novel protocols are under development for faster and more efficient analyses [51], [52].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com