In summary, we have demonstrated that U1-70K roams the cell nucleus rapidly ensuring its availability throughout the nucleus for taking part in splicing.
The accumulation and spread of Xist from an X chromosome inactivation centre (XIC) rapidly ensures chromosome-wide transcriptional silencing by triggering recruitment of inactive histone modifications and variants to the inactive X (Xi), and to DNA methylation sites on Xi (reviewed in Heard 2005).
Epithelial homeostasis, corresponding to a balance between epithelial cell loss and epithelial cell production, has to be maintained, particularly in the gastrointestinal tract (GIT) where the epithelium needs to be renewed extremely rapidly to ensure its function.
Ideally, such a procedure should (1) allow hundreds to thousands of cells to be processed rapidly; (2) ensure that no more than one cell is included in each amplification reaction yet maximize the number of cell-containing reactions; and (3) minimize contaminating DNA.
Following a myeloablative stem cell transplant, the hematopoietic system must repopulate rapidly to ensure the survival of the host.
"We need to be able to respond very rapidly to ensure a resumption of normal childhood activities for children and ensure that protection mechanisms and health standards are in place for them," said Mr. Perks.
Therefore, Monitoring of these clones through timely genotypic analysis would provide a way to identify suspected MDR-TB and XDR-TB cases more rapidly and ensure better tracing of contacts, with the aim of containing these strains, thereby avoiding a possible XDR-TB outbreak.
It just doesn't make sense to liberalize rapidly without ensuring that the financial system is sound enough to cope.
The bagel bits were rapidly eaten, ensuring mice obtained full and equivalent doses.
IT may be a commodity, and its costs may fall rapidly enough to ensure that any new capabilities are quickly shared, but the very fact that it is entwined with so many business functions means that it will continue to consume a large portion of corporate spending.
