Sentence examples for rapidly activating from inspiring English sources

These are prevented in mature IHCs by the expression of the rapidly activating large-conductance Ca2+-activated K+ current [ 85, 86] and the negatively activating delayed rectifier IK,n, carried by KCNQ4 channels [ 83] (see [ 87] for a review).

We next asked whether mature (P24) IHCs from Pls1 KO mice had normal biophysical properties, such as a rapidly activating large conductance Ca2+-activated K+ current (IK,f) and a current carried by KCNQ4 channels (IK,n) with an unusually hyperpolarized activation range (25).

70 It also blocks the inward rectifying K+ current (IK1) and rapidly activating component of the delayed rectified K+ current (IKr), but not the slowly activating component (IKs).

Of 8 patients in this group, 6 (75%) displayed the same polymorphism in KCNH2, which encodes the α-subunit of the rapidly activating delayed rectifier potassium current, IKr.

Since publication of ICH E14 and S7B over a decade ago, there has been a focus on drug effects on QT prolongation clinically, and on the rapidly activating delayed rectifier current (IKr), nonclinically, for evaluation of proarrhythmic risk.

The molecular bases of these bioelectric signals are ion channel proteins, transmembrane proteins that form rapidly activating and inactivating pores that permit ions to flow down their electrochemical gradients and across cell membranes.

Spore exposure rapidly activated the mitogen-activated protein kinase (MAPK) signaling pathways ERK, JNK, and p38.

p38 is rapidly activated at the onset of ischaemia and remains active during reperfusion.

Our results indicate that ERα activation by the specific ERα agonist PPT rapidly activates ERK1/2.

Macrophages are rapidly activated and polarized towards a M1 inflammatory phenotype ("classically activated" macrophages).

The simple Motorola camera app can be rapidly activated by a twisting gesture even when the phone is locked.