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Analyzing numerous expression datasets we revealed a striking global anti-correlation between rapidity of induction and mRNA stability, fitting the prediction of a kinetic mathematical model.
In the vast majority of the datasets analyzed, we found a highly significant anti-correlation between rapidity of induction and mRNA stability.
Indeed, in the vast majority of the datasets that we analyzed we detected a significant correlation between rapidity of induction and genomic transcribed length.
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Among induced transcripts, SOX2 was unique in the specificity and rapidity of its induction following EGFR inhibition.
50, 107 The magnitude and rapidity of its induction and its cooperative role in innate immune response, as well as its ease of measurement, all make CRP a common marker for inflammation.
These data suggest that the concentration of the challenging agent determines the rapidity and extent of induction of Trx.
This study not only elucidates the decreased efficacy of colloid solutions containing hydroxyethyl starch compared with normal saline in the induction of TH in vivo but also provides insight into complications associated with hydroxyethyl starch and re-emphasizes the importance of specific heat capacity of the solution with respect to rapidity of cooling during TH induction.
§ 1624.6 Postponement of induction.
The Problem of Induction.
Postponement of induction.
As the authors demonstrated, the thermodynamic effect of adding solute to a solution resulted in statistically significant differences clinically with respect to hypothermia induction and temperatures attained, as well as rapidity of cooling [ 2].
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