Regarding rapidity of effects, the CTG group had more individuals with a 50% reduction in total lesions by day 607777%) than the clindamycin lotion group (56%) (P = 0.003).
Overall, the current study suggests direct action of peripheral UAG because of the rapidity of its effect on the tissues we have examined.
To examine the rapidity of the effect of pharmacological manipulation on thermotolerance we developed an acute treatment with the PKG inhibitor KT5823.
First, the magnitude and rapidity of the effect produced probably account for some of the discrepancies reported in the literature concerning the development of spines during the first weeks of life.
The rapidity of this effect is consistent with a mechanism involving efferent modulation of the hair bundle's Ca2+ concentration through a change in the driving force on Ca2+, rather than diffusion of Ca2+ from intracellular stores to the hair bundle.
Thus, acute and chronic depletion of Emb activity causes pri-miRNA accumulation, with the rapidity of the effect arguing for a direct involvement of Emb in miRNA biogenesis.
The rapidity of the effect (within 30 minutes) rules out de novo transcription of an antioxidant factor, which suggests that it must rely on changes in abundance, post-translational modification, or localization of existing proteins.
And, thanks to the Internet's rapidity of ripple-effects that carry word from bloggers and enthusiasts to the world at large, the independent aesthetic and its artists have quickly had an impact on the Hollywood mainstream, in salutary ways.
The rapidity of 2CA effects therefore makes direct actions of the drug on T cells and/or APCs likely: both cell lineages express PAD (Liu et al., 2006).
Despite the magnitude and rapidity of these effects, the underlying mechanisms at the bone tissue level in stroke patients are unexplained.
Compared with high-load DEE, partial-load DEE caused greater responses in heart rate and T-wave morphology, in terms of both magnitude and rapidity of onset of effects, consistent with previous findings that systemic effects may be driven largely by the gas phase of the exposure atmospheres.
