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Topical application of HBP has previously been show to induce rapid leakage of FITC-labeled dextran in the hamster cheek pouch preparation [2].
In theory, the size of gold nanoparticles should be large enough in case of rapid leakage from tissue into blood capillaries; meanwhile, it should be small enough to escape capture by macrophages.
The extracellular conductivity in the P. digitatum suspensions with α-terpineol was higher than that of the control at all times, the values increased significantly after 30 min of exposure and positively correlated with the α-terpineol concentration (Fig. 2b), indicating rapid leakage of metal ions tested after the membrane disruption.
Whereas vessels in Ad-null control mice were well-defined and did not exhibit evidence of fluorescein leakage, vessels of sEng-expressing mice appeared more diffuse due to a more rapid leakage of the dye (Figure 3A).
There was rapid leakage in the dynamic model for the Mallinckrodt HiLo, the Sheridan Preformed and the Portex Profile group.
In the presence of rapid leakage around the cuff, none of the ETTs prevented contamination of the lung chamber.
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This rapid drug leakage is due to the presence of cholesterol and charged lipids in the liposomal bilayer.
This is relevant because prolonged accumulation of apoptotic cells may allow these cells to enter secondary necrosis, leading to rapid HMGB1 leakage.
It was initially reported to act like a lysosomotropic detergent, which in MCF-7 and WEHI-S cells induced rapid lysosome leakage and subsequent cathepsin-mediated cell death independent of caspases.
The sensor network consists both mobile and stationary sensors, which help to provide large-scale city areas monitoring with less sensors and provide more rapid and accurate leakage locating with GIS mapping.
For both these lipid mixtures, rapid and extensive leakage induction was observed with the tagged peptides (Figure 4B).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com