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The game between Teimour Radjabov of Azerbaijan and Alexei Shirov of Spain at the Leon Rapid Knockout Tournament in Spain, held from June 3 to 7, shows combinations sprouting up throughout.
The blitz tournament was a preliminary event leading up to a rapid knockout tournament beginning the next day.
Similar(58)
Ms. Kowroski's high kicks and backbends, especially when they come in rapid alternation, are knockout effects.
Transplantation of nuclei (NT) from engineered mouse ES cells is a potentially powerful and rapid route to create knockout mice, obviating the need for matings to obtain germ-line chimeras.
The efficient and rapid generation of gene knockout rats shows that using ZFN technology is a new strategy for creating gene-targeted rat models of human diseases.
Therefore, we have developed an assay that allows for the rapid measurement of gene knockout rates in 10's 100's of single cell clones.
The combination of rapid lethality of Lsd1 knockout mice and the relatively long half-life of lymphoid lineage cells did not allow us to study the long-term effects of Lsd1 loss in lymphoid cells.
In light of recent advances in the use of hPSCs for disease modeling, as described in the previous section, the demand for more efficient and rapid methods of gene knockout or modification has only increased.
In higher eukaryotes, random transposon mutagenesis has been used extensively to study gene functions through rapid generation of gene knockouts and knockdowns [12], [13], [14].
Zebrafish transgenesis methods have been well characterized, and the recent breakthroughs in gene editing with transcription-activator-like effector nucleases (TALENs) and CRISPR/Cas9 have enabled rapid and facile gene knockouts in zebrafish (Kawakami et al., 2004; Huang et al., 2011; Sander et al., 2011; Hwang et al., 2013).
In this study, a rapid single-step approach to knockout of a targeted gene in mice using zinc-finger nucleases (ZFNs) was demonstrated for generation of mutant (knockout; KO) alleles.
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