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After arthritis induction, wildtype and knockout mice developed rapid inflammation, indicated by acute joint swelling.
Details on the establishment and design of this rapid inflammation screening model can be found elsewhere [ 19, 20].
One pathway that has been associated with rapid inflammation and osteoclast formation is the leukotriene activation pathway [ 9].
This altered lipid composition may trigger a more rapid inflammation leading to atopic lesions in contrast to body sites that are not predisposed to AD lesions.
After arthritis induction rats developed rapid inflammation indicated by the acute joint swelling with a maximum between day 3 and 7.
The strain was chosen because of its high virulence proven in a mouse model [ 9], since we aimed to cause rapid inflammation due to the limited test period of the pig model.
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A mouse model with adenosine deaminase (Ada) deficiency has been established to develop a rapid pulmonary inflammation and progressive destruction of lung tissue that closely mimics many aspects of human COPD and other chronic lung diseases [ 13, 14].
RSV-associated AB in children presents very similarly to acute asthma: wheezing, rapid breathing, inflammation of small airways, and, in many cases, respiratory compromise leading to acute lung function failure [ 83].
This afferent signaling is rapid; peripheral inflammation induces c-Fos expression in the primary projection nucleus of the vagus nerve (nucleus tractus solitarius [NTS]) and secondary projection regions (including parabrachial, paraventricular and supraoptic nuclei, central amygdala, and bed nucleus of the stria terminalis) within 60 min of peripheral inflammatory challenge (10).
In our patient, overlying mucosa was preserved to minimize postoperative complications and promote rapid healing without inflammation, and during follow-up, she reported little inconvenience.
Patients adequately treated with high-dose systemic corticosteroids at the onset of the disease frequently have rapid resolution of inflammation with good visual outcome [1].
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