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As shown in Fig. 1, the process includes three main areas: the mixing and reaction area, the nucleation and growth area, and the rapid cold quenching area.
In the rapid cold quenching area, the cold quenching solution is delivered at the quenching solution inlet, to be mixed with the nanoparticle colloids at the Y mixer 2, following which the mix flows through the quenching channel.
The reactor consists of three regions: the mixing and reaction area from the inlets of 1 and 2 to Y mixers connected with channels shrinking from 200 to 30 μm, the nucleation and growth area with channel width of 60 μm and length of ~30 cm, and the rapid cold quenching area with the cold quenching solution delivered at the quenching solution inlet.
Rapid cold crystalloid infusion is the most frequent method; however, severe haemodynamic instability is its contraindication.
Glutamine regulation is of particular note as it is associated with both TPS expression (M. arctica) and rapid cold hardening (S. crassipalpis) [ 18].
Moreover, the protein of L. lancifolium increased with the rapid cold stimulus and then degraded into sugars with a faster reduction trend than the Oriental hybrids during the cold treatment.
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Synthesis of polyols is not exclusively assigned to diapause but is also often attributed to rapid cold-hardening [ 6, 79].
And as the arctic grows warmer at a rapid rate, cold snaps like the one sweeping half the country will become more frequent.
Some contigs that show a rapid response to cold also show altered expression following prolonged cold treatment.
Alternatively, protein phosphorylation and ubiquitination may serve as more rapid and flexible cold tolerance mechanisms for C. bungeana to adapt to the harsh cold environments.
The superiority of endovascular cooling is most likely due to the direct heat-exchange between catheter and blood, resulting in a rapid transfer of cold blood through the body, whereas surface cooling depends on relatively slow conduction of cold mainly through the tissue itself.
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