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The assay is based on a modified version of our "rapid catch and signal" (RCS) technology previously designed for the ultra-fast and sensitive analysis of genomic DNA sequences.
Microwave irradiation rapidly accelerates PA deposition onto the surface ("rapid catch"), significantly speeding up the MEF PA assay and resulting in a total assay run time of less than 40 min with an analytical sensitivity of less than 1 pg/ml PA.
Conversely, low birth weight followed by rapid catch up growth was associated with down-regulation of insulin signalling proteins which may predispose these animals to insulin resistance later in life.
However, there is some evidence that rapid catch up growth can be detrimental in terms of long term health outcome for low birth weight infants.
In addition, the sum of dioxins and PCB toxic equivalences in breast milk was associated with lower fat percentage, lower weight and length at birth, and increased early length and weight gain Z-score, i.e. rapid catch up growth.
Possible strategies to prevent excessively rapid catch up growth include limiting the extent of early growth failure, the promotion of breastfeeding and the use of a VLBW reference for growth monitoring in infancy.
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In China mass migrations associated with rapid catch-up growth and urbanisation are often blamed for causing instability.
"But the more fundamental issue is that the Japanese government and industry do not have a consistent strategy to deal with China's rapid catch-up".
This overall lack of convergence is surprising since in principle the more backward an economy the greater its scope for rapid catch-up growth.
The economy will be lifted by efforts to reduce administrative hurdles to investment and cut business overheads, but the rapid catch-up growth of recent years is no longer on the cards.
The same is true of India, where near-double-digit annual rises in GDP led politicians, and many investors, to confuse the potential for rapid catch-up (a young, poor population) with its inevitability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com