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Rap, rap!
RAP RULES -- Rap, rap.
As she flipped briskly through the children's CD's, saying, "Rap, rap, rap, no country in here?," their father, Anthony Biggins, stared in silent astonishment.
By Roger Angell The New Yorker, December 25 , 1978P. 37 Rap, rap!
It is noteworthy that although Raji cells are resistant to Rap, Rap treatment alone can diminish p-p70S6K, dissipate ∆ψm and inhibit glycolysis in Raji cells.
Mice were injected intraperitoneally daily with 3 mg/kg/d Rap (Rap group), 15 mg/kg/d Dex (Dex group), 3 mg/kg/d Rap plus 15 mg/kg/d Dex (Rap + Dex group) or PBS (Control group).
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Three types of the UGMs containing RAP (RAP-UGMs) as well as the UGMs of neat virgin aggregates (VA-UGMs) were tested at the temperatures of 40 °C, 22 °C, and 5 °C.
To this end, a series of laboratory tests including the repeated load triaxial test (RLT) and the quick shear test was performed on gap graded, continuous graded and coarse graded UGMs containing RAP (RAP-UGMs) as well as UGMs of neat virgin aggregates (VA-UGMs) at varying temperatures, 40 °C, 22 °C, 5 °C, and −10 °C.
Treatment with free RAP, RAP-loaded PHBHHxPEG NPs and RAP-loaded PHBHHxPEG NPs equally resulted in decreased p70S6K phosphorylation (Thr389), without affecting total p70S6K and total mTOR levels.
Fc fusion proteins were generated by fusing the extracellular domains of mouse LRP4 (residues 1 1650, LRP4-Fc), APP695 (residues 1 596, APP-Fc), or full length RAP (RAP-Fc) to the constant region of human IgG (Fc).
Cells were treated with 10 μM free RAP, RAP-loaded PHBHHx (100 μg ml-1) and PHBHHxPEG NPs (100 μg ml-1) which contained equal amounts of drug, respectively, for 48 h.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com