The one meta-analysis reference referred to as 'Other' used a novel approach developed by the authors of 'summary ranking' involving assigning a score to the rank order of toxicity in individual primary studies, and then combining the scores to provide an overall rank order for toxicity.
Individual naphthoic acid isomers demonstrated a rank order of toxicity with 1H2NA>2H1NA>2H3NA>6H2NA being more toxic.
Wang has demonstrated that the ranking of the toxicity of metal oxides to the test cells is as follows: TiO2 < Co3O4 < ZnO < CuO [14].
In vitro procedures, while economical, convenient and capable of ranking "relative toxicity," are uncertain predictors of specific lesions.
They rank each toxicant in terms of toxicity, exposure, and risk on a scale of 0 to 100, and this helps put the relative risk of this diverse group of agents in perspective.
Towards bridging this information gap, Cu and Zn were selected for the study in view of the fact that they have been ranked top in terms of toxicity among eight heavy metals (i.e. Cu > Cd > Zn > Pb > Ni > Fe > Mn > Al) in a biomonitoring study using M. tuberculata (Shuaimi-Othman et al. 2012).
Our results aligned with previous studies which strengthens our confidence in the toxicity ranking of all our tested phenolic compounds in which we found coniferyl aldehyde to be the most toxic phenolic compound.
With regard to E. coli the toxicity ranking of all surfactants studied in this work, referring always to their respective CMCs as the reference concentration, was: C10TAB>C12TAB>C14TAB>SDS>DDPS>Triton X-100.
Using in vivo tandem scanning confocal microscopy, this model was able to help distinguish between the toxicity ranking of 0.02%, 0.01% and 0.005% BAK concentrations by clearly showing the dose-dependent levels of epithelial deterioration.
The results showed that EC50 values of 30-min Flash Assay in tube and microplate formats were practically similar and correlated very well (log − log R2 = 0.98), classifying all analyzed chemicals, except nano CuO (that was more toxic in cuvette format), analogously when compared to the risk phrases of the EC Directive 93/67/EEC for ranking toxicity of chemicals for aquatic organisms.
