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Since for each of these analyses we are ranking and testing a large number of genes we must account for the possibility of false discovery.
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Unadjusted analyses used log-rank and Wilcoxon tests.
Chi-square, student-t, and Log-Rank tests and generalized estimating equations were used to compare groups.
Survival curves were plotted using Kaplan Meier estimates and were compared using log-rank tests and stratified log-rank tests.
Pearson's chi-square test, Wilcoxon rank sum test and Wilcoxon signed rank test were used for independent and paired comparisons as appropriate.
Wilcoxon's rank sum test and Wilcoxon's signed rank test were used for inter-group and paired comparisons, respectively.
Survival curves were examined by log rank test and Wilcoxon rank test.
Unadjusted P-values <0.05 were considered to be significant for the Mann–Whitney rank sum test and Spearman's rank correlation tests.
Categorical data were analyzed using the chi-square test and rank sum test.
Descriptive statistics, t tests, Wilcoxon rank-sum tests, and χ(2) tests were used to compare continuous or categorical values.
Descriptive analyses, Wilcoxon rank-sum tests, and Fisher exact tests were run.
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