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Then the server searches the index via SearchIndex, and eventually sends back the matched files in a ranked sequence according to the total relevance scores.
In the end, the server sends back the matched files in a ranked sequence, or sends top-k most relevant files if the user provides the optional value k. .
Enrichment estimates are calculated using common microarray summary statistics and a weighted Bayesian analysis of the ranked sequence space.
The curve obtained by plotting the precision at every position in the ranked sequence of items as a function of recall is called the precision-recall curve.
The key assumption implemented within SBSE is that both 'direct' miRNA down-regulatory events and siRNA off-target interference can be accurately assessed via estimates of 'seed' motif enrichment in a ranked sequence population.
When comparing the top 30 ranked sequence motifs for the QTT-A touchdown PCR experiment across all family A DNA polymerase amplification experiments (including PGT-A), the same 30 sequence motifs appear within the top 87 of 65,536 possibilities.
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We chose the highest ranked sequences from the round 5 pools that were also highly ranked in round 3.
In contrast, across all family A polymerase experiments, only 3-43-4% top ranked sequences contain this motif at the beginning of the runway (Table 2).
For the top 1% of ranked sequences, the average GC content is 79% for the family A DNA polymerases and 83% for the QHH-B DNA polymerase.
In contrast, QHH-B has a preference for "GC" or "CG" at the 5' end of the 6 N portion of the primer with 89% of the top 1% of ranked sequences containing this motif, while only 6-126-12%top ranked sequences from the family A experiments contain these sequences at their 5' end.
The sequence motif 3'- TC -5'- TC -5ferred by QHH-B DNA polymerase in the first two positions after the primer:template junction (on the template sequence) with 19% of the top 1% of ranked sequences sharing this motif.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com