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Finite as well as infinite ranges for model input factors are allowed.
The ranges for model parameters are listed in Table 2.
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By considering how the normalised parameters are scaled, we can constrain the plausible range for model parameters.
This outlines the importance of diffusion Model 2 where the mean of the Mg2+ departure process is indeed in the range of 10 ms as against the 1 μs range for Model 1.
Briefly, after initial values and plausible ranges for each model input parameter were established, repeated simulations were undertaken, each drawing different combinations of parameter values and projecting model outcomes with each set of parameter combinations.
Table 1 Nominal values and allowable ranges for the model parameters Parameters Nominal value Variation ranges TOP i (cmH2O) 30 (5, 60) Stiffness coefficient S i (cmH2O/ml2) 0.005(0.505, 0.5) Extrinsic pressure P ext,i (cmH2O) 28.8 (−28.828.8).
(1) The interesting ranges for the model parameters were determined in a preliminary exploration.
To assure the robustness of our results, we performed sensitivity analyses over wide ranges for all model parameters, and the results did not significantly impact our final conclusions.
These are obtained by randomly sampling from the uncertainty ranges for each model input parameter (Additional file 1: Tables S2-S4) [ 21].
A few days ago, Elon Musk pledged to "end range anxiety" for Model S owners by way of an over-the-air software update.
Complementary verifications on conventional reinforced concrete flat slabs are also undertaken to ensure the reliability of the selected ranges for key modelling parameters.
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