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Here, we were able to confirm these results in a larger patient group and for a larger range of uptake periods.
This time point was within the linear range of uptake for both dbcAMP-treated and -untreated cultures (results not shown).
In all experiments initial rates within the linear range of uptake were recorded over a total of 4 time points.
This is the only case encountered where there is a significant contribution of internal and external variability to flux variability in the physiological range of uptake rates.
Within the linear range of uptake, 200 µl samples were transferred on 0.2 µm nitrocellulose filters that were subsequently washed with 3 ml of reaction buffer.
Although subjects were given identical administered doses (40 ppm x min), there was a wide range of uptake, 0.6-4.9 microg/kg.
Similar(51)
With respect to the FaDu xenograft, there was a wide range of uptakes demonstrated with a standard deviation of 8.1, which is reflected in the variation of mean uptakes between experiments.
On the same range of uptakes, the RP at soma varies between 0 and 28 mV.
Accordingly, the ranges of uptake shown in Figure 2 do not represent the full variability of DDT uptake that may be found in the four populations.
Our goal is to convert the variability in reported DDT concentrations in exposure media into ranges of uptake and body concentrations without introducing additional sources of variability, and then to compare the ranges of estimated body concentrations with DDT levels from biomonitoring data.
We have previously reported on a series of strains, in which glucose uptake is mediated by different native and chimeric hexose transporters, which display a wide range of glucose uptake rates [ 3, 5, 6].
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