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Calculation results exceeding the range of reasonable values have been excluded from the study.
Other parameters can be chosen freely from a wide range of reasonable values.
In terms of ROC curves and AUC measures, proposed methods are insensitive to small deviations in prior strengths (within a range of reasonable values).
One-way sensitivity analyses were performed by varying key parameters (proportions of patients with CD4+ count ≤50 cells/µl, cost of fluconazole prophylaxis, cost of CRAG screening, and mortality rate due to cryptococcal meningitis) over a wide range of reasonable values to evaluate the impact of data uncertainties and to determine the robustness of the overall conclusions.
The grid started with the range of reasonable values, 0 - 1 for β and f and one to 200 days for α.
We extend this approach to a situation where μ is unknown and suggest to vary it systematically over a range of reasonable values.
Similar(51)
The parameter estimates can help, though, in finding the range of reasonable parameter values, e.g., to use them as starting values in NONMEM.
We selected a range of physically reasonable values for each parameter, and computed the set of TARs for each of a large combination of values within these ranges.
Our simulations show that the yearling tactic is favored across a wide range of biologically reasonable values for Sriver and τ.
This suggests that our chosen cut-off values may be acceptable for a broad range of reasonable CFN/CFP ratios.
We'll get a range of reasonable estimates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com