Sentence examples for range of noxious from inspiring English sources
TRPV1 is a cation channel activated by a range of noxious stimuli and highly expressed in nociceptive fibres.
It also controls cell survival, proliferation and differentiation gene expression induced by a wide range of noxious stimuli [20], [21].
In healthy controls, a wide range of noxious stimuli - including ice-cold water, contact heat and tourniquet ischemia - are all effective conditioning stimuli, producing increased pain thresh-olds throughout the body [ 7].
In order to study the response of C. elegans to a broad range of noxious thermal stimuli, we developed a novel assay that allows simultaneous characterization of multiple aspects of escape behavior elicited by thermal pulses of increasing amplitudes.
Several studies have shown that MKP1 confers protection against apoptosis induced by a wide range of noxious stimuli, including cisplatin, ethanol, ischemia/reperfusion injury, and H2O2, by attenuating the magnitude and duration of JNK signal (31, 50 50 50).
Like mammalian sensory neurons, polymodal md sensory neurons from Drosophila express multiple channel types including members of the Deg/ENaC, Trp and Piezo channel families, that are required for md neurons to respond to a broad range of noxious stimuli including chemical, mechanical, or thermal.
Skin is also flexible, can heal itself, and is sensitive to a wide range of temperatures and noxious chemicals.
Mouse knockout studies have revealed that TRPM8 is required for cold sensation over a broad range of innocuous and noxious cold temperatures [12] [14].
TRPV1 is also activated by a wide range of stimuli including noxious heat (>42°C), protons, endogenous lipoxygenase products and fatty acid amides [3].
Non-noxious movement is defined here as being within the normal working range of the joint, while noxious rotation refers to torque occurring outside the normal range but not severe enough to cause soft tissue injury.
TRPA1 is activated by colder temperatures (environmental temperatures < 17°C) than TRPM8 (96– 98), while TRPV1 is activated by a noxious range of heat (> 43°C) (99, 100).
