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And it stated that "dietary supplements are safe within a broad range of intake, and safety problems with the supplements are relatively rare".
The language contained within the Dietary Supplement Health and Education Act (DSHEA) also leads one to believe in the safety of virtually all dietary supplements ("dietary supplements are safe within a broad range of intake, and safety problems with the supplements are relatively rare").
For these essential metals there is a range of intake over which their supply is adequate to the body (Fe 8-18 Mn/day, Mn 1.8-2.3 1.8-2.3 Cu 0.9 mg/day, Zn 8-11 mg/day, Ni 0.5 mg/day) [1, 2].
Misclassification of ALA intake, especially within a relatively narrow range of intake, may have attenuated our associations.
The weaker associations found for raw and processed fruit and vegetables as well as for subgroup analyses may be a result of the narrower range of intake and limited number of participants.
Despite the small range of intake in our study, we did find an inverse association of ALA intake with incident stroke, which was most pronounced for ALA from salad dressings.
Similar(27)
The Linear Index Model has several benefits: it takes advantage of indexing nutrients according to energy requirements, thus providing levels of nutrient intakes that can be readily achieved by foods; it is based on population consumption data, thus providing a realistic range of intakes for the experimental conditions; and it ensures distinct contrasts in experimental conditions.
A similar plot for dietary manganese intake showed no association, even in the higher range of intakes (data not shown).
We simulated population-scale exposure by uniformly sampling from this range of intakes and milk production rates.
The range of intakes varied from 720 to 2621 mL/day; this diversity cannot be explained by environmental differences alone.
Variations in human diets across a plausible range of intakes have been shown to have no effect on blood pH.
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CEO of Professional Science Editing for Scientists @ prosciediting.com