Exact(2)
for a wide range of inhalation flow rates (i.e., 30-70 L/min).
In a quantitative study, using an Electronic Lung ™breathing simulator [ 35] to replicate patient-representative inhalation flow rates, the delivery performance of the DPI was investigated and showed consistent powder delivery across a wide range of inhalation parameters.
Similar(6)
High-efficiency dry powder inhalers (DPIs) were developed and tested for use with carrier-free formulations across a range of different inhalation flow rates.
To support both exposure and exposure response assessment, additional work is needed to measure specific congeners in the air of buildings with PCB sources to better characterize and understand the range of relevant inhalation mixtures and specific congener concentrations.
That evaluation derived the range (50th 95th percentiles) of inhalation risks, expressed as hazard quotients (HQs), the ratio of estimated intake to the reference dose (RfD).
The mathematical representation of particle transport in the airflow within the pulmonary system is of interest in a wide range of fields: from inhalation toxicology to infectious disease proliferation to drug delivery.
Over recent years the research focus within the field of respiratory drug delivery has broadened to include a wide range of potential applications for inhalation by delivering drugs not just onto the lung mucosa but across it.
Translocation of inhaled nanoparticles across the alveolar-blood barrier has been demonstrated in animal studies for a range of nanoparticles delivered by inhalation or instillation [ 5– 7].
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