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Because the degree of imprecision of the proxy variable is unknown, a range of imprecision levels were entered to explore the effect on the mercury regression coefficients.
The margin of equivalence, Δ, was defined as less than 12% points and the range -12% to +12% points thus is predefined as an acceptable range of imprecision (i.e., 95% confidence interval).
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The constant denotes the maximum acceptable range for imprecision in the answer.
The analytical sensitivity was 6 ng/mL, the intraassay imprecision within the range of 63 766 ng/mL was 4.8% and interassay imprecision within the range of 62 811 ng/mL was 6.7%.
In conclusion, we have developed an ELISA assay capable of measuring hepcidin in human serum samples at a range of 10 1500 µg/L with acceptable imprecision, linearity, recovery and specificity.
The analytical sensitivity of the IGFBP-3 assay was 20 ng/mL, the intra- and interassay imprecision within the range of 227 2703 ng/mL were 5.8 and 11%, respectively.
Considering the generally high concentration of synovial explant mediator release, an assay imprecision in the range of 26 to 360 pg/ml, depending on the cytokine, should not affect the overall associations with regard to imaging.
The second decisive result is that both assays show adequate intra-assay and inter-assay imprecision across the range of values measured in apparently healthy individuals and in critically ill patients in the ICU.
On the AxSYM platform (Abbott Labs, North Chicago, IL), the method has a measurement range of 3 100 pmol/L and a total imprecision of 6 9%.
Finally, although we considered a wide range of potential confounders, it is possible that imprecision in measurement could lead to residual confounding, and there remains the possibility of confounding by other unconsidered factors.
("Undocumented" is also rejected, on the grounds of imprecision).
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CEO of Professional Science Editing for Scientists @ prosciediting.com