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In sharp contrast to the range of deleterious effects on the NoAz genome given above, is the number of intact genes related to symbiotically important physiological processes.
We also produce these predictions for a range of deleterious mutations.
Their use requires re-evaluation in the light of a wide range of deleterious actions and retrospective studies suggesting harm.
Fetal alcohol spectrum disorders (FASD) is the umbrella term used to describe the wide range of deleterious outcomes following prenatal alcohol exposure.
The term "harmful" has been used to describe blooms of algae that can cause a range of deleterious physiological and environmental effects [ 12].
Insulin resistance leads to a wide range of deleterious metabolic changes, including the development of glucose intolerance, overt diabetes, hypertriglyceridemia, and hypertension.
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Influx and efflux transporters located at both barriers allow nutrient supply to the brain, while excluding a wide range of potentially deleterious compounds from this organ.
We can, however, fit a reflected gamma distribution to the more limited range of moderately deleterious mutations (−7 < S < −2) as shown in Figure 5.
Given the range of potentially deleterious effects that can be mediated by AngII (including depression of ACh release and inflammation), one can envisage possible consequences of over-production or post-translational modifications of ACE that could result in increased AngII production.
Tumor Necrosis Factor alpha (TNFα) is a pleiotropic cytokine extensively studied for its role in the pathogenesis of a variety of disease conditions, which is known to have a wide range of beneficial and deleterious effects in humans [1], [2].
We investigated the case with the highest probability of fixation (one duplicate gene with two copies) in more detail in fig. 3 B. We got very similar results for a wide range of population sizes and deleterious mutation rates.
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