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Thus, the derived kon value incorporates the overall binding process and does not give insights on the detailed mechanism, which for Ca2+ ions, may be quite complex, as evident by the wide range of association rates found in the organic and inorganic world.
We examined this for 28 protein pairs, representing the wide range of association scores exhibited by the 91 protein pairs.
In those studies, a wide range of association (0% to 88%) was found when bacteria isolated from the oropharyngeal region were examined for species similar to those found by fibre optic bronchoscopy or bronchoalveolar lavage of the lungs.
In an attempt to develop an approach that would be applicable across a wider range of association models, Lee et al. [ 28] proposed a linear combination of burden and dispersion score tests, constructed within the SKAT analysis framework.
Supplementary Figures 1 and 2 present power for a wider range of association models encompassing intermediate levels of allelic heterogeneity, where trait means are determined by the presence or absence of minor alleles at any causal variant, and by the proportion of causal variants at which a minor allele is present, respectively.
We considered a disease for which cases are categorized according to two sub-phenotypes, and examined a wide range of association scenarios, parameterized in terms of: (i) the minor allele frequency (MAF) of the causal SNP; and (ii) the heterozygous log-relative risk, under a multiplicative disease model, for each sub-phenotype.
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This modification technique allows precise, stoichiometric substitution with hydrophobic groups and accessibility to a wide range of association-driven conformations in aqueous media.
The range of associations evoked is broad — childhood, death, migration.
The word assembly carries a range of associations.
Meanwhile Ms. Kuhn's graphic vocabulary evokes a resonant range of associations: traditional Japanese landscape painting, Art Nouveau, German Expressionist woodcuts, contemporary comic books.
The image evokes a range of associations: a cemetery; a battlefield; Abramović's 1997 performance Balkan Baroque, 1997, when she washed 1,500 fresh cow bones.
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