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In CM patients initial VEP and SSEP amplitudes were in the same range of activation of HV (p>0.05), then habituated normally during stimulus repetitions.
A second and more interesting behavior was observed in all RBCs, specifically when the membrane potential was in the range of activation of Ih: taper occurred also at the low frequencies (Figure 3B, bottom two traces), resulting in a maximal response amplitude at an intermediate frequency.
This became a central idea - that there is a correlation between the affinity and range of activation of a gene.
Furthermore, in Figure 9 figure supplement 2 we show that there is difference in the range of activation of Nav current between WT and dKO cells that would account for the observed shifts in 0 current potential and rheobase.
Although early studies suggest a range of activation of other genes in a variety of other tissues, where these have been identified, they are mainly concerned with metabolic effects and can be regarded either as secondary to the profound metabolic changes or as primary and consistent with regulation of lipid metabolism through the PPARs.
Similar(55)
TWK channels have been implicated in defining temperature thresholds and ranges of activation of thermosensory neurons in mammals [ 30].
The effect of modifying the surface of CMK-3 via a range of activations to improve the formaldehyde removal efficiency was evaluated.
These rate constants correspond to a range of activation free energies of 13 16 kcal/mol.
Such heterogeneity is manifested in not only the origins of tissue-resident macrophages but also the wide range of activation states of macrophages.
This conjunctive contrast was preferred over the interaction term alone which could be driven by a wide range of activation patterns of no interest.
In order to examine potential pathways linking SHS exposure to CHD risk, we examine the epidemiological associations between SHS exposure, assessed by serum cotinine, with a wide range of activation markers of inflammation and hemostasis that existing data suggest could be part of the response to SHS exposure and are implicated in CHD risk in older men and women.
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