Initiation of ossification was abnormal in all mutant scapulae, with a range of abnormalities in evidence.
The numbers are still small, but out of 42 willing to have an ultrasound (28 refused), 12 were carrying babies with a range of abnormalities.
"We are seeing a great range of abnormalities," said Dr. Ian Wilmut, who as director of the Roslin Institute in Scotland led the effort to clone Dolly.
It includes a range of abnormalities involving the head of the thighbone and the receiving socket in the hip bone.
However, Chiari malformation represents a range of abnormalities and probably a heterogeneous grouping of disorders.
The first is the wide range of abnormalities that can be included under the umbrella of rotator cuff disease.
Blood samples collected from the cloned lambs after birth revealed a wide range of abnormalities indicative of kidney and liver dysfunction.
PWS patients may also demonstrate a range of abnormalities of sleep architecture and of breathing during sleep, and excessive daytime sleepiness (EDS).
There is a wide range of abnormalities which affect the skull base within the sella turcica, ranging from a persistent craniopharyngeal canal to trans-sphenoidal and sphenoethmoidal cephaloceles, many presentations of which are extremely rare.
The histological changes observed in the SM in OA generally include features indicative of an inflammatory "synovitis"; specifically they encompass a range of abnormalities, such as synovial lining hyperplasia, infiltration of macrophages and lymphocytes, neoangiogenesis and fibrosis.
