Sentence examples for range and potency from inspiring English sources
While mycobacterial lipases could conceivably mediate these effects, the range and potency of the lipase activities unleashed after infection were seen as more likely mediated by lysosomal lipases.
Inhibitory potencies, as given by the IC50 values, were all in the micromolar range and the potency of each compound did not differ significantly between species (Table 3).
Alpha-particle emitters are ideal in such a cell-specific targeting strategy because of their short, 50 100 μm range, and high potency.
In addition, by exclusively considering high-confidence activity data, it has been found that the most promiscuous bioactive compounds interact with two to five targets from the same target family, are predominantly active in sub-µM range, and display potency differences within one or two orders of magnitude against their targets.
The obtained derivatives were very potent inhibitors of both cholinesterases (EeAChE, EqBChE) with IC50 values ranging from sub-nanomolar to nanomolar range, and the inhibitory potency of the most promising agents was higher than that of the reference drugs (rivastigmine and tacrine).
In all instances VCN was found to significantly inhibit cell migration and invasion in the nanomolar range and with a potency similar to that of native CN.
Most of them exhibited low micromolar range of potency and very high efficacy.
Currently, there are eight inhaled corticosteroid molecules approved for clinical use that span a wide range of potency and other attributes.
This feature can affect the range of activities and potencies of HMGB1 preparations (recombinant or purified from natural sources) since the content of other components may vary.
Newly designed DPP4 inhibitors achieved sub-nanomolar potency range and demonstrated oral activity in vivo in mouse glucose tolerance test.
(q_i) is assigned a weight (w_i) given it's IC50 value (IC50qi) and the IC50 value of the least active molecule (IC50min): begin{aligned} w_i = log(mathrm {IC50_{min}}) - log(mathrm {IC50}_{q_i}) + 1.0 end{aligned} (1)This logarithmic weighting scheme ensures linear scaling over the entire potency range and attributes a weight of one to the least active molecule [10].
