In this analysis, the randomly enumerated virtual compounds fall within known drug shape space, but with a density distribution more closely resembling that of the DNP. Figure 8 Principal component ring assembly contour map using coarse aggregate shape descriptors p, q, and ψ.
Scaffold diversity of the randomly enumerated compounds was assessed by calculating the Tanimoto distance (ECFP_4) for each ring assembly against all others in the set.
In Bushenyi District, households were randomly selected from an enumerated list of all the households in each village.
The percentage of apoptotic cells was calculated by dividing the number of ApopTag-positive cells over total number of nuclei enumerated from randomly selected ten microscopic fields (10X) of individual samples using ImagePro.
One lymphocytic focus per specimen was randomly selected for enumerating the number of positively stained cells.
The total households enumerated in the randomly selected villages were 452 with the following distribution: 56 (18), 41 (14), 64 (21), 76 (20), 87 (25), and 128 (44) households from Amibara, Awash Arba, Gewane, Halaideghe, Sideha-Faghe, and Worer, respectively, where the numbers in brackets show the number of households surveyed in each village.
In the first stage of sampling, villages were enumerated and selected randomly with probabilities proportional to each village's population.
Using probability proportional to size of the wards (in each site) ten cell units were then selected randomly and their households were enumerated and mapped to allow random selection.
Once data collection was complete, the lead investigator on this component of the study enumerated the road segments, randomly selected 25%, and re-assessed the segments to validate the initial measures.
Community controls will be randomly selected from lists of previously enumerated children residing in Demographic Surveillance System areas (Kenya, The Gambia, Bangladesh), where birth registries exist (South Africa), or from lists of households in areas with existing registries of households (Thailand).
Live and dead sperm cells were enumerated from fifteen separate, randomly-selected visual fields.
