Molecules either in the cytosol or bound to the scaffold protein will be randomly activated by a cytosolic activator.
Because of spontaneous activity and STDP, synaptic strengths fluctuate, randomly activating and deactivating synapses; therefore, the functional connectivity of the network fluctuates, allowing patterns of connections that would otherwise be inaccessible in a static architecture.
By this means we were able to unravel the most evident activation status of PP2A at the IKK complex and to predict a mechanism underlying UVB-induced PP2Ac inactivation: In unstimulated cells PP2A is most likely associated with the IKK complex in a constitutively active fashion, where it presumably controls dephosphorylation of randomly activated IKKβ.
Spike-time-dependent plasticity in the offspring layer was then used to infer the underlying topology of the parental layer, on the basis of activity received from the parental layer neurons as they were randomly activated.
These crazy adventures our minds have while we are sleeping may be a product of our memories randomly activating so as to keep them fresh, and of the mind seeking connections between all the things we have recently experienced.
Noise was introduced in the model by randomly activating, at every iteration, a small number of nodes with a given probability.
This scenario could change however if some randomly activated prey genes in the host nucleus were selected and fixed in the population [47], [48] allowing them to survive within populations.
The results showed that muscle fibers were randomly activated by both LFS and HFS, independent of the exerted force.
In Section 1, we raised the possibility that NMES randomly activates type I and type II fibers, leading to muscle hypertrophy.
Furthermore, we exploited the multicolor Confetti reporter system, a powerful tool for clonal analysis, in which Col2a1-Cre ERT-mediated recombination randomly activates one of its four reporters (Supplementary information, Figure S1F).
