However, there are equivocal results from only two randomized trials studying the effect of such intervention.
Neither of the above-mentioned randomized trials studied one of the new low-MW HES solutions.
The results of recent randomized trials studying postmastectomy radiation show that improved loco-regional control improves OS.
These results were confirmed in randomized trials studying the efficacy of multicomponent delirium prevention programs in postoperative patients [ 57] and geriatric inpatients [ 58].
Nevertheless, this type of surgery reflects the surgery performed in most randomized trials studying adjuvant treatment in early stage ovarian cancer [ 17], while suboptimal surgical staging is a well recognized problem in early ovarian cancer [ 24, 25].
In another prospective, double-blind, placebo-controlled, randomized trial study carried out in five hospitals in Taiwan, 166 hemodialysis patients completed the 56-day study.
As a consequence, an international randomized trial study comparing RT + surgery versus surgery alone with quality control of excision mesorectum [ 10] was conducted in 1805 patients.
This assumption is based on a randomized trial study whereby a strategy-trained group was compared with an active-stimulation control group, with the latter not manifesting significant cognitive gains (Vas et al. 2011).
HRQoL was, however, a prespecified secondary endpoint in a second phase 3, open-label, randomized trial (study 301) that evaluated eribulin versus capecitabine as first- to third-line treatment in pretreated patients with MBC [ 12].
