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The data for this study came from the control group of a cluster randomized trial (Trial Registration: ClinicalTrials.gov ID NCT01960738).
A randomized trial (trial number NCT01896908) will investigate the effects of sodium and fluid restriction on neurohormonal activation in HF patients with preserved ejection fraction.
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In our systematic review we excluded non randomized trials, trials in which superficially penetrating needles were used as sham acupuncture, and trials where electrical needle stimulation was performed in the treatment arm.
A recent randomized controlled trial trial of anakinra (1 mg/kg/day; maximum 100 mg/day) versus placebo in 50 patients with JIA was unable to demonstrate significant efficacy of the drug.
81 In the AGELESS (aliskiren for geriatric lowering of systolic hypertension: a randomized controlled trial) trial, 82 the drug was found to be more effective and better tolerated than ramipril in patients with ISH.
The authors and their investigative team are completing a randomized clinical trial (Trial Registration NCT00567333) to compare the clinical and cost-effectiveness of individualized treatment for LBP in either a monodisciplinary chiropractic or multidisciplinary integrative care setting.
In a randomized VEGF clinical trial (RAVE trial) with AdVEGF-121, there was no clinical therapeutic effects observed [9].
However, a recent large prospective randomized trial (Split Trial) reported no difference in AKI incidence in patients receiving either balanced crystalloids or isotonic salt solutions [31].
For example, in a prospective, multicenter, open-label randomized trial (PRORATA trial) involving 630 non-surgical patients with suspected bacterial infections [35], patients in the PCT group had significantly more antibiotic-free days.
Dr. Combes is the primary investigator of the EOLIA trial (NCT01470703), a randomized trial of VV-ECMO supported in part by MAQUET.
Overall, 3 different variables were independently randomized trial by trial in each experiment: apparent viewing distance of the scene (3 values), figure type in the near background (static or dynamic), and ball descent duration (5 values).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com