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Participants will be randomized to Wobenzym or placebo in a 1 1 ratio using a pre-generated randomization list with variable block sizes.
The trial sequence used in each list was randomized with the following constraints: No variant of attributes or objects was repeated within three consecutive trials and in no block were nogo- and catch-trials presented in the first two trials or in succession.
The order of blocks was randomized with the constraints that no identical stimulus type (scale, pattern A, pattern B) occurred in direct succession and that stimuli with the same order of major keys occurred maximally two times in direct succession.
Within each block of trials, target and non-target probability was randomized with the constraints that the last five stimuli of each block (i.e., stimuli presented just before the thought-probe) were non-targets.
The order of verbs and conditions was randomized, with the constraints that: (i) immediate repetitions of trials belonging to the same condition could not occur, and (ii) that verbs were not repeated within blocks of 90 trials.
The presentation order of the problems with correct or incorrect answers was randomized with the constraint that no more than 2 correct (or incorrect) responses occurred in a row; participants were not informed about this ordering strategy.
Trial order was randomized with the constraint that the same emotional category could not be presented more than three times in a row.
Trial order was randomized with the constraint that the same combination of emotional category and old/new status could not be presented more than three times in a row.
The pairs of digits to be compared were randomized, with the constraint that the pairs in any given trial were all different.
The presentation order was pseudo randomized with the constraint that no more than two identical conditions were presented in a row.
The order of the blocks was randomized, albeit with the constraint that each speller type was introduced first in the overt attention condition, not in the more difficult covert attention condition.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com