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A randomized exercise trial in older women: increased activity over two years and the factors associated with compliance.
BACKGROUND: The Inhibition of Metallo Protease by BMS-186716 in a Randomized Exercise and Symptoms Study in Subjects With Heart Failure (IMPRESS) clinical trial randomized patients with congestive heart failure to a daily regimen of either omapatrilat or lisinopril.
Therefore, we investigated factors influencing participation in a randomized exercise intervention trial for breast cancer patients.
To our knowledge, only five randomized exercise trials included breast cancer patients during adjuvant radiotherapy [ 63- 67].
Willingness of breast cancer patients to participate in a randomized exercise intervention study differed by sociodemographic factors and health status.
Non-metastatic breast cancer patients were systematically screened for a randomized exercise intervention trial on cancer-related fatigue.
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The BEST-Participation-study was an observational study embedded in the BEST-study, collecting information on factors potentially influencing willingness to participate in a randomized exercise-intervention trial.
For example, if feasible, a multi-arm, randomized controlled exercise intervention trial that includes participants with different types of AORC may be appropriate.
However, the results of previous randomized controlled exercise intervention trials have reached conflicting and underwhelming conclusions regarding the effects of ground reaction and/or joint reaction force exercise on BMD at the femoral neck (FN) and lumbar spine (LS) in postmenopausal women [ 9- 33].
The Physical Activity and Lymphedema (PAL) Trial is a recently completed randomized controlled exercise intervention trial that recruited 295 breast cancer survivors (141 with lymphedema at study entry, 154 at risk for lymphedema at study entry).
Seven subjects randomized to exercise and 4 control subjects completed the study.
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