In a well-conducted, but underpowered, multicenter, randomized, controlled pilot of delirium prophylaxis in medical ICU patients with antipsychotics (either haloperidol or ziprasidone vs. placebo) did not show any benefit with either haloperidol or ziprasidone compared with placebo [93].
This prospective randomized controlled pilot trial was designed to evaluate whether prescreening embryos for aneuploidy can improve clinical outcomes in infertile patients undergoing IVF, without limiting to poor prognosis patients.
Cyclic functional electrical stimulation does not enhance gains in hand grasp function when used as an adjunct to onabotulinumtoxinA and task practice therapy: a single-blind, randomized controlled pilot study.
This study reports a multicenter, randomized, controlled, pilot trial of moderate systemic hypothermia (33°C) vs normothermia (37°C) for 48 hours in neonates initiated within 6 hours of birth or hypoxic-ischemic event.
This prospective, two-site, randomized, controlled pilot study assessed the feasibility of an enhanced physical activity (EPA) intervention in hospitalized children and adolescents receiving treatment for a solid tumor or for acute myeloid leukemia (AML), and assessed different statistical techniques to detect the intervention's sleep and fatigue outcomes.
The present study, the Improving Maintenance of Physical Activity in Knee Osteoarthritis Pilot Trial (IMPACT-P), was a single-blind two-arm, randomized controlled pilot study designed to contrast the effects of a group-mediated cognitive behavioral (GMCB) exercise intervention with those of traditional center-based exercise therapy approach (TRAD) in older, knee OA patients.
Masked randomized controlled pilot trial.
Study design and protocol: This was a masked randomized controlled pilot trial on infants with elevated alveolar-arterial oxygen gradients (A-aDO2) admitted to the Regional Neonatal ICU of the University of Alabama at Birmingham, a regional perinatal center.
Our study was an open-label, randomized, controlled pilot with a sample of about 90 infants.
