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Therefore, a randomised effects model for meta-analysis was applied in order to minimise the effect of clinical heterogeneity.
21 Possible sources of discrepancies between baseline and randomised effects of hormone therapy in the women's health initiative have been reviewed and include both greater duration of treatment and possible confounding by differences in lifestyle in the baseline data.
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As comparison groups (treated for cervical intraepithelial neoplasia with a particular procedure versus non-treated) were non-randomised, effects and effect sizes cannot be attributed with certainty to the treatment alone.
We carried out formal checks for statistical heterogeneity between the trials by summarising randomised treatment effects for each trial using odds ratios obtained from the individual patient data.
'Fish Creek' were sampled as part of a larger split-plot sampling designed consisting of six blocks [ 21] of which we only investigated the (randomised) contamination effect.
Since we compare strategies starting with LNG-IUS or endometrial ablation, patients who are not satisfied with the (randomised) treatment effect can choose another treatment, or opt for hysterectomy.
In a prospective randomised trial, the effects of an intermittent compression hand pump vs. cryotherapy were compared on reduction of postoperative hand swelling and gain in finger movement after distal radius fractures.
By conducting a randomised clinical trial, effects in terms of causality would have been stronger supported.
In randomised trials, the effects on cancer mortality persisted for several years after the end of the 5- to 9-year intervention period [ 2].
Databases of electronic health records (EHR), such as those managed by the Clinical Practice Research Datalink (CPRD), provide the opportunity to conduct a large pragmatic randomised trial evaluating effects of antibiotics in patients with mild or moderate acute COPD exacerbations [ 6].
We have recently investigated in a randomised study the effect of trastuzumab on patients' clinical outcome.
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