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A pragmatic stepped wedge randomised cluster trial with repeated cross section design will be conducted.
A stepped wedge randomised cluster trial with repeated cross section design will be employed [ 54, 55, 59].
In 2008, we undertook the baseline survey for an HIV risk reduction randomised cluster controlled trial (RCCT) in Botswana, Namibia and Swaziland (ISRCTN register, 2008).
This randomised cluster controlled trial tested the effect on uptake of informed discussion of vaccination costs and benefits, without relying on improved health services.
There are possible ways to overcome this, provided there is forward planning and strong government commitment, such as undertaking a stepped-wedge trial, a type of pragmatic randomised cluster controlled trial [ 16].
This was a cross-over randomised cluster trial that involved 21 schools located in as many municipalities in the province of Cuenca and Ciudad Real, Castilla-La Mancha region (Spain).
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We included intervention (randomised, cluster-randomised, quasi-randomised and non-randomised comparative studies) and observational studies (cohort, case-control, cross-sectional, case series and case reports).
To prevent contamination, we will randomise clusters on practice level.
We propose to randomise clusters in four groups of clusters on a 1 1 ratio.
We will randomise clusters after recruiting the study sample and seeking informed consent from the residents.
All women of reproductive age (15 45 years) resident in the study area randomised by cluster of residence.
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