Sentence examples for random turnover from inspiring English sources

Random turnover of mtDNA increases heteroplasmy variance through folliculogenesis and germline development.

These observations thus correspond to results expected from the random turnover from the BDP model.

This quantity is the sum over all later phases of the product of the length of that phase and the rate of random turnover, thus giving a measure of total random turnover.

(B ) This mechanism results in heteroplasmy variance increasing both due to stochastic partitioning at divisions and due to random turnover.

The 'turnover' parameter, described in the text, is ∑ ​ i = 3 6 τ ′ i ν i, a measure of the total random turnover in the mtDNA population.

Briefly, this result arises because the BDP model produces increasing variance both due to early cell division stochasticity and later random turnover.

Although non-cytolytic cure of infected hepatocytes have been approved to occur, it is estimated that a minimum of 0.7 1 and approximately 2 complete random turnovers of the hepatocyte population of the liver occurs during the resolution of WHV infection in woodchucks and HBV infection in chimpanzees, respectively.

They were considered random, full turnover, and class-based storage assignment policies.

Here we show that this observation is compatible with (and expected from) our proposed model of random mtDNA turnover.

Our inferred mechanism of random mtDNA turnover is thus compatible with the observations of a labelled subset of mtDNAs in the BrU incorporation assay in Wai et al. (2008)—we would expect to see roughly the observed labelling proportion simply due to the likely rates of random mtDNA turnover inferred at that stage of development.

Using approximate Bayesian computation and mouse data, we find most statistical support for a combination of binomial partitioning of mtDNAs at cell divisions and random mtDNA turnover, meaning that the debated exact magnitude of mtDNA copy number depletion is flexible.