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The tumbling of rigid molecules that is, the random rotations of molecules in solution plays a key role in the relaxations observed by nuclear magnetic resonance, particularly protein NMR and residual dipolar couplings.
In CDOCKER, random ligand conformations were generated from the initial ligand structure through high-temperature molecular dynamics followed by random rotations.
This suggests that subjects who experienced random rotations had learned an adaptation strategy that was specific for the structure of the environmental variability they encountered during training.
One group experienced random rotations (rotation angles between −90° and +90°); the other group experienced random shearings (shearing parameters between −2.0 and +2.0; see Supplemental Experimental Procedures for details).
Starting from the Tan IIA of input configuration, 10 different orientations were randomly generated by translating the center of the ligand to the grid within the receptor active site, and performing a series of random rotations, and then docked into the protein (3O96), i.e., moved into the center of the grid.
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Take the relevant features, rotate them with a random rotation matrix, and add them as redundant features by substituting features.
For the first time a profound interpretation of CNF diffraction patterns is given, proving the rotational disorder of the turbostratic structure and suggesting a random rotation between successive graphene cones.
Second, two strategies to equalise and optimise the workload (conduction ratio and switching frequency) of each valve are developed: 1) the circular queue schedule strategy ensures uniform workload of each valve and 2) the circular queue with random rotation schedule strategy can further decrease the switching frequency drastically by introducing randomness.
The selection will be done by random rotation among the four active district judges.
Patrons take a number to take a turn, with five different short plays — none more than 10 minutes long — being performed in random rotation by five performers.
The three training procedures were; Structured Mix before Random Rotation, Random Rotation Only, and Combined Blocking.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com