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To prevent selection bias, a statistician who is not associated with the study generated a list of random numbers using a random numbers table, the randomization schedule was concealed from community health service center staff until allocation.
The study statistician will prepare a random numbers table to permit randomization in permuted block sizes of 3 and 6, stratified by surgeon.
An independent statistician performed the randomization by creation of a random numbers table and use of color-coded (for stratification), opaque, numbered envelopes.
The randomization sequence was derived from a random numbers table and the allocation was recorded on a card sealed in a sequentially numbered opaque envelope.
Randomization will be by computer generated random numbers table, with group allocation on a folded piece of paper in an opaque envelope, packed by a staff member independent of the project team.
Five studies did not report the use of allocation concealment during randomization (9– 15, 15), while another used a random numbers table (14).
Randomization was by blocks for four from a random numbers table.
Randomization was carried out using Pocock's first column in his random numbers table [ 23].
Individual sampling stations (located at river kilometers) were selected using a random numbers table and alternated in orientation to each shore when possible.
Randomisation was performed using a random numbers table.
A blocked random numbers table was computer generated.
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